It was cancelled after only two issues, in spring 2004, before the company declared bankruptcy and ended production on all their titles.
Charon and his opposite counterpart Appolyon, are revealed to have been the human scientists who organized the Great Transition as seen in Crux.
Charon secretly engineered the device to impart him with incredible god-like power, even as the rest of the human race ascended to a higher form themselves.
After meeting Appolyon, several of the characters from the Negation title travel to Han-Jin, the world depicted in Brath, Way of the Rat and The Path.
The series ends with a cliffhanger, as Evinlea leads the Negation assault on Elysia, home of The First.