[9] The show's initial premise focused on three households, made up of 12 core characters, living in Ramsay Street, dealing with everyday life with humour and drama.

[16][17] In 2005, Neighbours celebrated its 20th anniversary and over twenty former cast members returned for a special episode, which saw the characters sitting down to watch a documentary about Ramsay Street and its residents.

Daniel Bennett, the new head of drama at Network Ten, announced that the crux of the Ramsay Street story would go "back to basics" and follow a less sensational path than of late with the emphasis on family relations and suburban reality.

Digital Spy revealed that the week-long 6,000th episode celebrations would see the wedding of regular characters, Donna Freedman (Margot Robbie) and Ringo Brown (Sam Clark).

[31] Nick Spooner, the head of Ten digital media said "This is part of what we call our 'three-screen approach' – broadcast, online and mobile – and it is intended to build viewer engagement with a show and our brand.

[33][34] Of her departure, Bower told Colin Vickery of the Herald Sun, "I love Neighbours, it is a wonderful show and because of this I felt it was important that fresh eyes and brains take over to keep this Australian icon contemporary.

[37][38] Network Ten and Channel 5 aired a documentary special titled Neighbours 30th: The Stars Reunite, which featured interviews with current and former cast members, including Kylie Minogue, Jason Donovan and Guy Pearce, reflecting on their time on the show.

"[44] Following the departure of Sonya Rebecchi in 2019, actor Eve Morey stated that the killing off of her character was a measure to reduce production costs for the program as part of its new negotiations.

[49] In response to the threat to the series' future, a fan-run petition on Change.org asking Channel 5 to reconsider its decision was launched,[50] which was signed by over 50,000 people,[51] including cast member Lucinda Cowden.

[54][55] Neighbours actor Jackie Woodburne said in an interview with The Project that the cast were "in shock" upon hearing the news,[56] while Alan Fletcher said the soap needs "a hero" to save it and Cowden explained that "the idea of no longer playing Mel is devastating.

"[57][52] Numerous current and former cast members, such as Annie Jones, Natalie Bassingthwaighte and Geoff Paine,[58][59] expressed their sadness online, specifically Rob Mills, who called on the Morrison government to step in and help.

[60] After the decision to cut the show's funding by British broadcaster Channel 5, an online campaign was launched trying to get Barry Crocker's version of the Neighbours theme song to number one in the UK charts.

[69] A study conducted shortly after the final episode aired in Australia and the UK found that fans experienced considerable feelings of grief and loss at the conclusion of the series, with viewers having formed strong connections and bonds with their favorite characters.

Lauren Anderson of Amazon Studios said, "With the power of streaming, we're able to offer a catalogue of thousands of Neighbours episodes for new audiences to discover this legendary series and current fans to relive their favourite moments.

[101][102] In November 1992, the characters Rick Alessi (Dan Falzon) and Debbie Martin (Marnie Reece-Wilmore) visit London to attend a Michael Jackson concert.

[109] The following year, a sixth storyline was filmed on location in London, featuring Amanda Holden and Sophie Ellis-Bextor alongside regular cast member Jemma Donovan (Harlow Robinson).

[126] The move caused some viewers to speculate that the soap was on the verge of being cancelled, but April Rose Pengilly (who plays Chloe Brennan) confirmed that the rumours were not true.

[134] Michael Grade, the channel's then controller, was advised by his daughter to move the morning broadcast repeat to a late afternoon slot, as she and her friends kept missing it due to them being at school,[134] which took place from 4 January 1988.

[142] Channel 5's commissioning editor Greg Barnett explained that closing the transmission gap would reduce spoilers and the number of viewers watching the show illegally online.

[177] On 7 July 2014, Todd Spangler from Variety reported that FremantleMedia International had signed a deal with U.S. subscription service Hulu giving it exclusive rights to the most recent season of Neighbours.

Ten revamped the show, adding several new, younger cast members including Jason Donovan as Scott Robinson and Kylie Minogue as Charlene Mitchell.

[200][201] Programming chief David Mott stated, "Last night's strong result for Neighbours already suggests the audience will follow the folks from Ramsay Street to their brand new neighbourhood on Eleven.

[11] Single father, Jim Robinson (Alan Dale) lived next door with his children, Paul (Stefan Dennis), Julie (Vikki Blanche), Scott (Darius Perkins) and Lucy (Kylie Flinker).

[228] When Network Ten picked up the show and revamped it, they brought in new and younger actors including Kylie Minogue as Charlene Mitchell and Jason Donovan, who replaced Darius Perkins as Scott Robinson.

Early cameos included former Skyhooks musician Red Symons, Warwick Capper, Molly Meldrum, Chris Lowe of Pet Shop Boys, and Clive James.

[241][242][243] During the 2000s and 2010s, the series featured appearances from The Wiggles, Shane Warne, former Spice Girls singer Emma Bunton, Little Britain's Matt Lucas and David Walliams, The Veronicas, Daryl Braithwaite, wrestler Dave Bautista, Lily Allen, Russell Brand (performing his own monologue), Katherine Kelly Lang, André Rieu, Paula Abdul and Jamie Lawson.

[276] The new titles also introduced a group shot of the entire main cast at the end of the sequence, initially showing a pool party and later moved to Lassiters Lake.

[296] The first full-length spin-off, a five-part series entitled Neighbours: Erinsborough High, was distributed on video on demand and catch up TV services My5 and 10 Play in November 2019.

Un Posto al Sole is based on an original format, developed by Wayne Doyle with Adam Bowen, Gino Ventriglia e Michele Zatta, with different settings, characters, stories, and contents in comparison to Neighbours.

Titled Cobbers, the sketches featured a group of stereotypical Australians dressed in swimwear conflicting with Everett's suit-wearing middle class British personality.