[7] The first settlers of European descent in the area were James O'Neill and his party, who arrived around 1845, looking for a location to build a sawmill along the Black River.

[9] A Winnebago Indian boarding school was operated by the Evangelical and Reformed Church on the west side of Neillsville from 1921 to 1957.

Poor health had forced Steele to retire from architecture in late 1946, leaving his eldest son William L. Steele Jr. and partner Josiah D. Sandham in charge of the practice.

Steele had come to Neillsville to live with one of his daughters, Sallie (Mrs. Thomas S. Noble Jr.), and died at her house on March 4, 1949.

42.3% of all households were made up of individuals, and 22.8% had someone living alone who was 65 years of age or older.

38.1% of all households were made up of individuals, and 21.3% had someone living alone who was 65 years of age or older.

[21] In addition, the Chippewa Valley Technical College has a regional center in Neillsville, which offers GED, associate's degree, and continuing education classes.

The High Ground is a veterans' memorial park located west of Neillsville.

The building is now home to local radio station WCCN/WCCN-FM and a gift shop.

Chatty-Belle is a large cow statue located on the ground of the Wisconsin Pavilion.