Nelson and Colne was a constituency in Lancashire which returned one Member of Parliament (MP) to the House of Commons of the Parliament of the United Kingdom from 1918 until it was abolished for the 1983 general election.

It was largely succeeded by the Pendle constituency.

1918–1950: The Boroughs of Nelson and Colne, the Urban Districts of Barrowford, Brierfield, and Trawden, and the detached part of the parish of Foulridge which was bordered on the north, west and south by the Borough of Colne.

1950–1983: The Boroughs of Nelson and Colne, and the Urban Districts of Barrowford, Brierfield, and Trawden.