[3] Nadolo was the overall top try scorer of the 2014 Super Rugby season competition while playing for the Crusaders, scoring a try in both the semi-final and final.

[4][5] He changed his name to Nemani Nadolo later as an adult, adopting his mother's maiden name in 2009 instead of the surname of his father who had left the family home when he was young.

[4] After featuring for Perth Spirit in the 2007 Australian Rugby Championship (as Ratu Siganiyavi),[5] he headed east to play for Randwick in 2008.

His club rugby season was punctuated by selection for the Australian Under 20 team for the 2008 IRB Junior World Championship, where he crossed 7 times in 5 matches to be the tournament's leading tryscorer.

[7] Nadolo was one of the finds of the 2008 season, with his hard-running and try-scoring prowess earning the powerhouse wing a Super 14 contract with the Waratahs.

Nadolo's size, style of play and Pacific Islander background drew him comparisons to Jonah Lomu when he signed for the Waratahs in 2008.

Nadolo signed with French Top 14 team Bourgoin-Jallieu for the 2010–11 season, but transferred to England's Exeter Chiefs in January 2011.

[15] He went on to play 14 Super Rugby games, including 12 starts, in his first season and was the equal top try scorer with Israel Folau, notching 12 tries.

[23] Nadolo made his Test debut in 2010 when selected in the 24-member Fiji team for a one-off match against Australia, followed by the 2010 IRB Pacific Nations Cup.

A week later in the 2014 IRB Pacific Nations Cup, he faced Tonga scoring 20 points including a try and kicking 6 conversion and a long-range penalty.

Nadolo returned for Fiji in 2015 and played on the wing against the Māori All Blacks in Suva but while scoring a try, he damaged his pectoral muscles which ruled him out for 6 weeks and the 2015 World Rugby Pacific Nations Cup.