Nemunėlio Radviliškis is a town in Biržai district municipality, in Panevėžys County, northern Lithuania.

In 1729, Gruzdas, a priest of the Dominican monastery of Palėvenė, broke into and vandalised the Evangelical Reformed churches in Nemunėlio Radviliškis and Papiliai.

In 1655, the Swedish Field Marshal Levenhaupt moved with part of his army from Kuoknese to Nemunėlio Radviliškis and established a camp there.

During the Kościuszko Uprising in 1794, rebels were hiding in the forests of the surrounding area, as the local population was being forcibly taken into their army.

During the years of Lithuanian press ban The Nemunėlis and Apasčia Association of Book smugglers was founded in secret.