Neodrillia albicoma is a species of sea snail, a marine gastropod mollusk in the family Drilliidae.

The spiral sculpture consists of extremely fine, close-set, regular threads, uniform over the entire surface, but scarcely visibly developed in the first four whorls, which appear polished to the naked eye.

Other transverse sculpture comprises only fine lines of growth which are not parallel to but more oblique than the aforesaid ribs, and reticulate prettily the spiral threads.

The aperture is more than one third as long as the shell, polished within, with a deep broad notch, slightly in advance of the suture, whose edges are produced and considerably reflected.

A broad, not very thick, continuous band of white callus from the end of the columella over the body passes into the reflected margin of the notch.