[4] The known range of Neotricula aperta is from just south of Kratié in the Mekong river of Cambodia to Kong Lor in Savannakhet of central Laos.

[4] The snails are restricted to areas where the current is moderate (around 2 × 103 m3s−1), the water is clear and the bed rock forms (almost flat) platforms where agal aufwuchs is extensive.

[4] The snail Neotricula aperta requires hard water to provide the calcium needed for rapid shell growth as populations re-establish in the Mekong river each year following the annual flood.

[4] Neotricula aperta grazes the algal epilithon and therefore, unlike species such as Biomphalaria (African vector of other kind of schistosomiasis), cannot survive in areas where sediment is depositing and preventing the growth of the algae upon which it feeds.

[4] Indeed, ecological studies of Neotricula aperta have shown that this snail is found only on stones covered with fine sediments and that this species is highly sensitive to silting.