Prior to the Bosnian War, he worked in Konjic as clerk of town planning, construction and housing, as well as communal services, marketing and catering inspecting.

From 1988, Nikšić was employed in Konjic, where he worked as clerk of town planning, construction and housing, as well as communal services, marketing and catering inspecting.

From 1995 until 1998, Nikšić was vice president of the executive committee of the Municipality of Konjic, and from 1998 until 2000 he was head of General Administration, Housing and Communal Services and Inspections.

[2] The political crisis occurred after the 2010 general election when major parties were unable to come to an agreement to form the new government.

[4] On 28 April 2023, following interventions by High Representative Christian Schmidt due to months of political deadlock after the 2022 general election, Nikšić succeeded Fadil Novalić to once again serve as Federal Prime Minister.

[5] Nikšić pledged that economic reform, further infrastructure development and fight against corruption would be the main goals of his government.

[6] Former Federal Prime Minister, Fadil Novalić, who Nikšić succeeded in April 2023 after Christian Schmidt's intervention, at first refused to concede the power, and continues contesting his forceable deposing as illegal and unconstitutional.