[3] Their parents were Flaviana Benedetti and Garry Nervo, who had established a dental practice together in 1975 in Whittlesea, Victoria, Australia, north of Melbourne.

[6][7][8] The twins studied at Genazzano FCJ College, a girls school in Kew, where they participated in rowing and swimming, but were mainly involved in music.

[11] When the sisters were sixteen, a modeling agency took an interest in the pair, but Liv Nervo stated in April 2012 that music "was always the focus" for them.

[14] Initial recognition for the pair occurred following the single "Negotiate with Love", written for British pop singer, Rachel Stevens, which reached tenth position in the United Kingdom (UK) music charts in 2005.

[16][17] The duo went on to write for Kesha, Richard Grey, Sophie Ellis-Bextor, Ashley Tisdale and the Pussycat Dolls.

[18] The move reaped quick rewards when the new publisher arranged a writing session with Kelly Rowland through Universal A&R Max Gousse.

[18] The group co-wrote Guetta and Rowland's number one dance hit, "When Love Takes Over" which went on to win a Grammy Award, in addition to reaching the top position on numerous charts around the world.

The twins also worked on records for Kylie Minogue's eleventh Aphrodite,[24] Britney Spears,[25] Cheryl Cole, Sophie Ellis-Bextor, Armin Van Buuren[26] and for Kelly Rowland's self-titled, third studio album.

Also, from Collateral, was "The Other Boys" featuring Kylie Minogue, Jake Shears and Nile Rodgers, was a remix single that was released on 23 October 2015.

[39] In 2018, the duo's collaboration with Sofi Tukker, the Knocks and Alisa Ueno on the former's “Best Friend” (used in a 2017 television commercial for iPhone X) gave Nervo their first number one on Billboard's Dance/Mix Show Airplay Chart in its January 20, 2018 issue.

[44] In October 2021, Nervo's song "Horizon" was used in a mini art film created within the Las Vegas mega-club Omnia.

[45] In May 2013, the duo filmed scenes for the soap opera One Life to Live that included dialogue in addition to their performing DJ roles.

The sisters also open up about the pivotal moments that have influenced their personal and professional growth and reflect on how motherhood and grief have inspired their latest compositions.

[53] The Nervo twins collaborated with the child advocacy group Hopeland on a campaign to end the practice of children separated from their parents and moved to orphanages for profit.

[61] They also played at the Electric Daisy Carnival in Las Vegas and the Spring Awakening Music Festival in Chicago in June 2012.

In July 2012, the twins DJd again at Belgium's Tomorrowland and performed at the Electric Zoo event in New York City, over the American Labor Day weekend.

Held at the Oracle Arena in Oakland, California, US, Spookfest is an event organised by the Live 105 radio station and its electronic dance music specialty program "Subsonic".

[76] In December they played at ZoukOut, one of Asia's biggest music dance festivals[77] Nervo performed at the second edition of summerland festival in Colombia on 5 January and at the fourth annual Avila Beach Party on 23 May along with Cash Cash and Manufactured Superstars[78] Nervo performed at Digital Dreams 2014 in Toronto, Ontario, Canada along with many others like Dimitri Vegas & Like Mike, Eric Prydz and Tiesto.

In addition, Nervo also performed at Escapade 2014 in Ottawa, Ontario, Canada alongside well-known DJ's, such as Kaskade, Carnage and Zeds Dead.

Nervo performed at the Forever Festival, Freedom Hill Amphitheater, Sterling Heights Michigan on 19 September 2014.

Nervo had also played during the Road to Ultra event in Paraguay, Asuncion, being this their first time stepping on Paraguayan soil.

In April 2015, it was announced that Nervo will release a single with Kylie Minogue, Jake Shears and Nile Rodgers soon and will be featured on the upcoming album Collateral.

In June 2016 Nervo begun their Nervonation summer residency at USHUAIA in Ibiza, with dates running until the season closed in September.

Nominated for ‘Best Party DJ’ at the inaugural World Dance Music Radio Awards at the Azteca Stadium on 29 March, Nervo played at the award ceremony in front of a crowd of thousands and a radio audience of over 10 million listeners across Spain, Central and South America and the Caribbean.