Nesoryzomys narboroughi is a rodent in the genus Nesoryzomys from Fernandina Island in the Galápagos Islands.

Nesoryzomys indefessus, a related extinct species, was found on Indefatigable Island.

Some consider the two to be subspecies of one species, in which the Fernandina form would be Nesoryzomys indefessus narboroughi;[1] however, N. narboroughi is now considered distinct.

[2] Due to Fernandina Island's small size, as well as vulnerability to invasive species, N. narborughi was rated by the IUCN Red List as a Vulnerable species.

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