The house was built in 1872 for Edwin S. Nettleton, a member of the Union Colony of Colorado who designed canals.

[2] When Nettleton died in 1901, the house was acquired by Alexander Mead.

His daughter, Ella Mead, was a female physician who "established one of the first birth control clinics" in the United States in 1920.

It has been listed on the National Register of Historic Places since April 2, 2002.

This article about a property in Colorado on the National Register of Historic Places is a stub.