Located in the Shephelah between Be'er Ya'akov and Ness Ziona, it falls under the jurisdiction of Gezer Regional Council.

[1] Kibbutz Netzer Sereni was founded in 1948 by Holocaust survivors liberated from Buchenwald concentration camp, who had established themselves in 1945 as "Kibbutz Buchenwald", an agricultural collective designed to prepare Jews for life in Palestine, the first such Hakhshara group established in Germany after the war.

[2][3][4][5] The kibbutz was established on the land of the Palestinian village of Bir Salim, which was evacuated in 1948 under orders from authorities in nearby Ramle, despite requests from the local mukhtar to the Haganah asking for protection.

He was parachuted into Nazi-occupied Italy in World War II, only to be immediately captured by the Germans and executed in Dachau concentration camp;[8] in Hebrew netzer means sprout, shoot or branch.

[8] The 2023 Israeli musical film Victory focuses on two fictional couples from Netzer Sereni.