14595783961ENSG00000169752ENSMUSG00000032311Q8WWG1Q9WTX4NM_138573NM_032002NP_612640NP_114391Neuregulin 4 also known as NRG4 is a member of the neuregulin protein family which in humans is encoded by the NRG4 gene.

[5][6][7] The neuregulins, including NRG4, activate erb-b2 receptor tyrosine kinase 4 (ERBB4) to initiating cell signaling through cytosolic tyrosine phosphorylation.

[7] Loss of expression of NRG4 is frequently seen in advanced bladder cancer while increased NRG4 expression correlates to better survival.

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