U.S. Route 95 (US 95) is a major U.S. highway traversing the U.S. state of Nevada from north to south directly through Las Vegas and providing connections to both Carson City (via US 50) and Reno (via Interstate 80).

[4] U.S. Route 95 enters Nevada near Cal-Nev-Ari in Clark County and heads north towards Railroad Pass, where it meets Interstate 11 and US 93.

In downtown Winnemucca, US 95 turns north in the general direction of Paradise Valley, leaving Interstate 80 Business to follow SR 289 east.

North of Winnemucca, US 95 meets the eastern terminus of SR 140, which connects to Lakeview (U.S. Route 395) and Klamath Falls, Oregon and the Pacific Northwest.

[9] A proposal to extend US 95 south to Winnemucca was considered by AASHO in 1937; however, action was deferred due to incomplete sections in Oregon.

AASHO reconsidered the idea at its meeting on June 28, 1939, as part of a larger plan to extend the highway south to Blythe, California.

[9] The route was marked along several preexisting state highways as follows:[10][11] The Nevada portion of US 95 covered a distance of approximately 686 miles (1,104 km).

The northern segment of State Route 1A had been previously established running north from Fallon to connect with US 40 southwest of Lovelock.

This new alignment eliminated the need to drive west to Fernley and then double back eastward, shortening the highway's length by about 26 miles (42 km).

Reaching the city limits of Las Vegas, the road changed names to Fremont Street as it headed into downtown.

The route followed Las Vegas Boulevard northward briefly before going west on Bonanza Road (now SR 579).

The former alignment on Fremont Street and Boulder Highway is now SR 582, though some portions of that route are now being decommissioned by the state and turned over to local entities for maintenance.

The interstate highway would primarily follow the US 95 corridor through central and northwestern Nevada, extending to I-80 near Reno and Sparks via Tonopah.

In 2018, the Nevada Department of Transportation had initiated public outreach regarding its long-range planning efforts to narrow down options for the future I-11 corridor.