According to Marom, during the 18th and 19th centuries, the area belonged to the Nahiyeh (sub-district) of Lod that encompassed the area of the present-day city of Modi'in-Maccabim-Re'ut in the south to the present-day city of El'ad in the north, and from the foothills in the east, through the Lod Valley to the outskirts of Jaffa in the west.

[2] Over the years, it attracted families of airline pilots due to its proximity to the airport.

In 2003 it elected and established the Neve Monosson Local Administration, in order to preserve the community's unique social and cultural autonomy within a municipal merger with the neighboring town of Yehud that created the joint Yehud-Monosson municipality.

[citation needed] The community, which has its own elementary school, country club, scouts troop, sports hall, culture hall, library and support system for the elderly, is characterized by its uncommon level of volunteering activity.

[citation needed] Israeli archaeologists have discovered Chalcolithic remains in the area of Neve Monosson.