The album contains guest appearances by Akon, Autumn Rowe, Bow Wow, Felecia, Fleetwood Mac (sampled), Mariah Carey, Swizz Beatz, The Game, Twista, will.i.am, and Yolanda Adams.

Producers include Akon, DJ Toomp, Jermaine Dupri, Mally Mall, Neo Da Matrix, Pretty Boy & Bradd Young, Street Radio, Swizz Beatz, The Individuals, Ty Fyffe, and will.i.am.

As a trio Krayzie, Layzie, and distant third Wish are a solid crew, able to deliver good weekend numbers like "Bump in the Trunk," "Lil Love," and "C-Town" (they never forget Cleveland) along with polished gangsta tracks like "I Tried."

Much of the credit for the revitalized sound on their seventh LP, Strength & Harmony belongs to producers like Swizz Beatz, will.i.am, and Akon, who deftly flip samples from sources as disparate as Bobby Womack and Fleetwood Mac.

Bone Thugs-N-Harmony’s lyrics, too, are impressively crafted, tempering rough bluster with humble spirituality and calling to mind their classic mid-’90s hits — a pleasant surprise after years of diminishing returns."

On the Neo Da Matrix–tracked gem “C-Town,” fellow spitfire Twista tag teams with the crew atop an airy bed of whistles and sonic hypnosis.

Backed by newcomers the Individuals’ intense strings, all three members’ flows reach new levels of velocity, especially Krayzie's: “I’m coming at you with a sound like thunder, strike like lightning/Hit them and they wonder where these thuggish ruggish niggas came from.” Matt Baron of XXL (magazine) gave the a "L" (Large) rating, stating "Don’t call it a complete comeback, however.

Further downgrading the album are scattered, drowsy soundtrack lapses (DJ Toomp's bland bass guitars on “Sounds the Same,” for example) and stunted creativity (the “been there, shot that” murder taunts of “9mm”).