The Main Post Office in the city of New Brunswick in Middlesex County, New Jersey, United States was built between 1934 and 1936.

It was listed on the National Register of Historic Places on July 18, 1984, for its significance in architecture, art, and communications.

[1][3] This building replaced the previous post office located on Albany Street and built in 1903.

The new building is built with red brick and brownstone and features Neo-Georgian architecture.

The artist George Biddle created several murals depicting the American Revolutionary War in New Brunswick as part of the Works Progress Administration (WPA) Federal Arts Project.