[2] It is included in the Federal Aviation Administration (FAA) National Plan of Integrated Airport Systems for 2017–2021, in which it is categorized as a non-hub primary commercial service facility.

From 1959 to 1971, the airport hosted the main operational base of Capitol International Airways, a supplemental air carrier, which had a fleet of DC-8 aircraft engaged in charter flights.

In 1968, AL had four daily departures using their F-27s nonstop to Philadelphia, Washington's National Airport, Atlantic City, and Trenton.

[12] United Airlines, while on a campaign to serve all 50 states, began service to Wilmington in 1984 with one-stop jet flights to Chicago.

USAir Express carrier Crown Airways provided scheduled service to Parkersburg, West Virginia, briefly beginning in 1992 before its sale to Mesa Airlines in 1994.

Shuttle America would eventually discontinue its independent operations and become a commuter affiliate of United Express and Delta Connection.

Delta Connection carrier Atlantic Southeast Airlines flew 50-seat Canadair CRJ regional jets on two daily roundtrip flights.

Delta Air Lines ended the Wilmington flights on September 6, 2007, leaving Delaware without any airline service.

On March 8, 2008, Skybus Airlines began Airbus A319 jet flights from Columbus, Ohio, and Greensboro, North Carolina, to Wilmington.

On July 1, 2013, Frontier began Airbus A320 jet service at Wilmington, initially with flights to Denver, Chicago-Midway, Houston-Hobby, Orlando, and Tampa.

[2] The airport terminal building has no jet bridges, thus requiring air stairs in order to board and disembark aircraft.

In the year ending December 22, 2022, the airport had 46,057 aircraft operations, average 126 per day: 80% general aviation, 12% military, 8% air taxi, and <1% airline.