Beginning in April 2021, the show was anchored by Keilar at the CNN DC Studios and by Berman at 30 Hudson Yards in New York.

The program began in June 2013, where it was presented by three anchors: Chris Cuomo, Kate Bolduan and Michaela Pereira.

On September 15, 2022, it was reported that New Day would be replaced with a panel-styled morning news program, hosted by Don Lemon, Poppy Harlow, and Kaitlan Collins.

Pereira departed the show on April 29, 2016, and anchored a live, two-hour daytime news program on CNN's sister channel HLN, which began in July 2016.

[6] From 2013 to 2019, the New Day set was located in Studio 71 at Time Warner Center, and consisted of a red/orange-colored faux brick background, highlighted by spot lighting, with inset LCD panels, glass-fronted cubicles, and a glass-topped desk on a central podium.

[citation needed] Mediaite ranked New Day as the best morning cable news show of 2018, saying Avlon's "Reality Check" segment is "a winning addition to the show — his comprehensive fact-check segments are a standout, and a welcome feature on television in a current era lacking in reality-based news coverage.