Dr. Maurice J. Lewi, a physician and educator, then serving as Secretary to the New York State Board of Examiners, was named the first president of the school.

Completed in 1978, the new training facility, the Foot Center of New York, provides clinical services to the community and continues to be affiliated with the college.

[4] As of January 2025, Touro University officially bought the NYCPM property in Harlem for $42 million as part of its acquisition of the school.

The third and fourth years feature clinical rotations at The Foot Center of New York in general podiatry, biomechanical orthopedics including gait lab, podopediatrics, physical therapy, wound care, and radiology focusing mainly on the foot and ankle.

NYCPM offers a dually registered joint DPM/MPH degree, in which the Master of Public Health portion is completed at and awarded through the Icahn School of Medicine at Mount Sinai.