The New York State Psychiatric Institute, located at the Columbia University Irving Medical Center in the Washington Heights neighborhood of Manhattan, New York City, was established in 1895 as one of the first institutions in the United States to integrate teaching, research and therapeutic approaches to the care of patients with mental illnesses.

Ira Van Gieson, Adolph Meyer, August Hoch, Otto Kernberg, Lawrence Kolb, Edward Sachar, Herbert Pardes and Jeffrey Lieberman.

In December 1929, the institute opened as a unit of the Columbia-Presbyterian Medical Center, owned and operated by the state of New York under the supervision of the Department of Mental Hygiene.

[5] It is connected by walkway bridges to the high-rise Lawrence G. Kolb Research Laboratory at 40 Haven Avenue at West 168th Street, built in 1983 and designed by Herbert W.

In 1953, Harold Blauer, a patient undergoing treatment for depression at the institute, died following an injection of the amphetamine MDA given without his permission as part of a U.S. Army experiment.