The western terminus is at an intersection with NY 37 in Oswegatchie, just west of the Ogdensburg city limits.

NY 68 was re-extended to its current length in 1982 as part of a highway maintenance swap between New York State and St. Lawrence County.

The vast majority of NY 68 is maintained by New York State Department of Transportation (NYSDOT).

Along the way, it passes residential homes and several commercial businesses, parallelling the MacDonald-Cartier Freeway (Highway 401) to the north in Ontario and NY 37 to the south.

NY 68 crosses a branch of the St. Lawrence River in downtown Ogdensburg, passing Crescent Park soon after.

[13] In March 1967, the New York State Senate approved a bill to swap maintenance of the two roads.

[14] That April, Governor of New York Nelson Rockefeller signed the bill to transfer roads, with NY 68 being designated as a less desirable alignment.