The Hartford, Providence and Fishkill Railroad opened in 1850; it shared the H&NH right of way north of Newington, but diverged to the south and ran to New Britain.

The depot was served for years by a single agent, John C. Sternberg, who sold tickets, handled freight and Adams Express packages, and threw switches to direct trains at the junction.

[4] Passenger service to New Britain ended in 1959, and Newington closed completely at this time - trains to and from New Haven no longer stopped.

The remaining buildings were added to the National Register of Historic Places on December 22, 1986, as one of five sections of the Newington Junction Multiple Resources Area.

[3] The listing of "Newington Junction Railroad Depot" includes the 1891 NY&NE station, 1890 NYNH&H freight house, and a short section of the Amtrak-owned right of way between them.

[4][7] Newington Junction is a bus rapid transit stop on the CTfastrak line, which follows the original HP&F route from Hartford to New Britain.

[11] In February 2017, the state announced an additional $50 million in funds, including money to complete design of Newington station.