Established in 1963 by the Ngee Ann Kongsi, NP is renowned for its business programmes and central focus on entrepreneurship education.

NP's alumni include founder and former CEO of Creative Technology Sim Wong Hoo, co-founder and CEO of Carousell Quek Siu Rui, co-founder and President of Carousell Marcus Tan, co-founder and CEO of Secretlab Ian Ang, 18th Golden Horse Award for Best Leading Actor Alan Tam, and 50th Golden Horse Award for Best Narrative Feature and Best Original Screenplay Anthony Chen.

[1] In December 1990, Ngee Ann Polytechnic applied for a radio station broadcasting on AM, with its programmes produced by mass communication students, concentrating on talk shows.

[2] There are a total of nine academic schools providing 39 full-time courses:[3] The polytechnic also offers part-time programmes for adult learners through the CET Academy.

[4] The polytechnic was conferred the Singapore Quality Class Star Award for demonstrating business excellence.