At age 16, he joined his father and participated of the military campaigns directed by Juan Lavalle and José María Paz.
In 1854 Oroño sent a letter to president of the Argentine Confederation Justo José de Urquiza with a proposal for the institutional organization of Rosario, which was approved.
Together with Marcelino Freyre, Oroño represented Santa Fe in the Assembly that wrote the Argentine Constitution in 1853.
In 1862 Oroño was elected member of the Chamber of Deputies, but in 1865 he resigned, after being chosen to replace Patricio Cullen as governor of Santa Fe Province.
When he finished his mandate in 1868 he was elected national senator, and from his seat he promoted the expansion and population of the country.