Growing up in Capricorn Park, Cape Town, Dlamini's first sport was running, which he took up in 2009 along with his twin sister Nikita.

Dlamini turned professional in 2018: at that year's Tour Down Under, the first UCI World Tour race of his career, he won the King of the Mountains jersey, becoming the first black South African to win a major classification in a World Tour race.

[5] On 27 December 2019, Dlamini was assaulted by rangers at the Table Mountain National Park where he was training and suffered a broken arm during an altercation.

[6] He was selected to represent South Africa at the 2020 Summer Olympics.

[7] He rode in the 2021 Tour de France, becoming the first black South African cyclist to ride the Tour, but was eliminated after finishing outside the time limit on the ninth stage.