Nicholstown-Newtown (usually called Nicholstown or Newtown) is a small area to the north-east of Southampton's city centre.

The area is formed of residential streets with a typical parade of small shops and services; the exception is its central feature, Royal South Hampshire Hospital, established in 1843–1844.

The Church of St Luke was constructed in Newtown in 1853 using a gift of land and money from Thomas Chamberlayne.

[4] Frustrated with the inaction of the city council and police, over 2,000 people marched from Derby Road to the civic centre.

Following this "march of neglect", the Queen visited the area and a cash injection of half a million pounds followed.