Nick Lowe and His Cowboy Outfit was reissued in 2000 by Demon Music Group.

Nick Lowe and His Cowboy Outfit incorporates more of a roots rock feel than Lowe's previous albums, including nods to Tex-Mex music ("Half a Boy and Half a Man"), 1950s guitar instrumentals ("Awesome"), and country music (via a cover of Faron Young's "Live Fast, Love Hard, Die Young").

The album also includes a cover of Mickey Jupp's "You'll Never Get Me Up in One of Those", which had been previously recorded by Lowe's former Rockpile bandmate Dave Edmunds (the Edmunds version can be heard on his album Twangin...).

Rockpile had also played as backing band on the Jupp original, on his 1978 album Juppanese.

Despite good reviews (including a B+ grade from critic Robert Christgau), Nick Lowe and His Cowboy Outfit only reached No.