In 2017, after having been featured on Topic's hit "Home" (2015), he released his breakthrough solo single "Rooftop", which reached the top five in German-speaking Europe, Poland and Slovakia, as well as number one in the Czech Republic.

It also received several certifications, including triple gold by the German Bundesverband Musikindustrie (BVMI) and quintuple platinum by the International Federation of the Phonographic Industry Switzerland (IFPI SWI).

Santos' debut studio album, Streets of Gold, was issued in October 2018 and yielded other moderately successful singles alongside "Rooftop", such as "Safe" (2018) and "Unforgettable" (2019).

Another top 10, "Would I Lie to You", followed in 2021 in the territory, the same year as Santos released the single "Leere Hände" ("Empty Hands") to great commercial success in German-speaking Europe under his last name only.

Apart from his solo releases, Santos has co-written or produced songs for a number of German artists, including Bushido, Shindy, Helene Fischer and Mark Forster.