Nicolás Grille (born 13 December 1974) is a Uruguayan former rugby union international.
[2] Grille was born in Montevideo and raised in the city of Paysandú.
During his international career, Grille competed locally for Trébol Paysandú.
By the time he left international rugby he was playing with Argentine club Hindú.
[3] Grille played his rugby as an amateur and was employed as a sales manager.