He served as Head of the Corps of Special Inspectors of the Presidency and Coordinator of the National Film School of Venezuela, appointed by his father.

[1] Though Maduro Guerra sought a career in music, he placed 77 of 235 on a waiting list for the National Experimental University of the Arts and decided to abandon the idea.

[5] On 21 July 2014, the PSUV held a party congress and voted for Maduro Guerra to be a delegate for the El Valle Capital District.

[7] On 11 August 2017, US President Donald Trump said that he is "not going to rule out a military option" to confront the government of Nicolás Maduro and the deepening crisis in Venezuela.

[9] His father President Maduro and his wife Cilia Flores were accused of nepotism for allegedly placing family members in Venezuelan government positions.

At the wedding of José Zalt, a Syrian-Venezuelan businessman that owns the clothing brand Wintex, on 14 March 2015, Maduro Guerra was showered with American dollars at the gathering in the luxurious Gran Melia Hotel in Caracas.

On 8 June 2017, officers of the Bolivarian Intelligence Service (SEBIN) detained Morales and her husband when they were about to aboard a private flight to Aruba in the La Chinita International Airport.