Nicolò De Cesare (born 31 January 1990) is an Italian footballer who currently plays as a defender for Grottammare.

Born in Ascoli Piceno, Marche, De Cesare started his career with Internazionale in 2004.

In the 2007–08 season, he left for the reserve team of Pro Sesto along with Andrea Bavena, Samuele Beretta, Mattia Dell'Aera, Davide Tremolada,[1] Fabio Perissinotto (since January) and Luca Profeta (since January).

In the next season, he left for Monza along with Paolo Campinoti, Luca D'Errico, G.Kyeremateng, Domenico Maiese, Mirko Santoro, D.Tremolada, Stefano Tresoldi, Maximiliano Uggè,[2][3] Niccolò Scaccabarozzi and Francesco Poltero (since January).

[4] In August 2009, he was signed by Seconda Divisione club Mezzocorona.