In 1997, she shared an Emmy Award nomination with several producers of Chicago Hope in the category "Outstanding Drama Series".
In 2009, Prestwich and Yorkin joined the crew of new ABC science fiction drama FlashForward as consulting producers and writers.
The show follows a team of FBI agents investigating a global blackout that gave victims a vision of their future.
Prestwich and Yorkin co-wrote the teleplay for the episode "Gimme Some Truth" based on a story by Barbara Nance.
In 2019, Yorkin was on the negotiating committee for the "WGA-Agency Agreement", and joined other WGA members in firing her agents as part of the guild's stand against the ATA after the two sides were unable to come to an agreement on a new "Code of Conduct" that addressed the practice of packaging.