In 1999 Parkinson commenced drawing Dennis the Menace initially alternating his interpretation of the character with artist David Parkins, until 2003 and in 2010/11 with Jim Hansen, Barrie Appleby and Tom Paterson.
In 2003, The Dandy asked Parkinson to freshen up the look of the terrible toddlers Cuddles and Dimples, taking over from the original artist, Barrie Appleby and changing the appearance of the characters and the personalities of their parents.
He drew the record sleeve for Kaiser Chiefs's single "The Angry Mob" and Count Arthur Strong's Christmas CD.
He drew the stamps collection for both Isle of Man Post office in 2018 [6] and The Royal Mail in 2021 [7] He is one of the few commercial cartoonists in the UK to operate a studio system with assistants.
From 2015 he began attending Comic cons regularly (having refused all but one offer in 2008, until then) with Nika Nartova where they do sketches for attendees, give interviews and talks and demonstrations.