Her father worked in the Tourism department for Uttar Pradesh & later Uttarakhand state government, her mother ran a design institute in New Delhi and she is the eldest of 2 sisters.

Niharika featured in several print campaigns, fashion magazines, music videos and decided to drop out of college and move to Mumbai to pursue a full time career in the entertainment business in 2003.

[13][14] Singh featured in Times of India's 2005 list of Most Desirable Women and continued her modeling career until she started getting offers to act in Bollywood films.

[21][22][23] The films were never made and she remained locked in the contract until singer Himesh Reshammiya approached her to play the role of a haughty heiress opposite him in A New Love Ishtory to be produced by T-Series (company) and directed by John Matthew Matthan.

[43][44][45] Singh played a mysterious ingénue with a shadowy past, for which she earned rave reviews for her performance and a nomination for the most promising newcomer at the 21st Screen Awards.

The series explores a wide range of social issues affecting modern youth including casteism, child neglect, corruption, homophobia, religious discrimination, and income inequality in India.

[77][78][79] Additionally, she was appointed the goodwill ambassador for Rotary Blood Bank in 2005 at the behest of the Governor of Uttarakhand Sudarshan Agarwal and a garden was named after her in Mussoorie.

"[94][95][96][97] In November 2018, Singh wrote an essay addressing the Me Too movement as a dalit woman in the entertainment business which was posted by journalist Sandhya Menon on Twitter.