Nikola Fraňková (born 7 February 1988) is a Czech former tennis player.

On 9 March 2009, she reached her highest WTA singles ranking of 249.

Fraňková won four $25,000 doubles events in 2006, and in 2009 participated in three WTA Tour qualifying draws, at Warsaw, Portorož and Tashkent, losing in the first round in each.

She and Ágnes Szávay were the runners-up to Victoria Azarenka and Marina Erakovic in the 2005 Australian Open girls' doubles.

Fraňková won the girls' doubles at the 2005 US Open, with Russian Alisa Kleybanova.