Nikola Hristić (Sremska Mitrovica, 10 August 1818 – Belgrade, 26 November 1911) was a Serbian politician who served as Prime Minister of Serbia for four terms.

[2] On 15 June 1862 Hristić was a witness to what began as a skirmish but developed into a major conflict between the Serbian Gendarmerie and Turkish troops at Belgrade.

The Timok Rebellion was successfully crushed, and the leaders of it, most notably Nikola Pašić of the People's Radical Party, fled to Bulgaria.

Nikola Hristić was married to Juliana (born Hadži-Jovanović), the granddaughter of Toma Vučić-Perišić, one of the leaders of the Serbian Revolution.

Hristić's son – Kosta (1852–1927) – was a lawyer, diplomat and minister of justice; his daughter Poleksija (1861–1933) was married to Laza Lazarević, the famed Serbian physician writer.