He was the Minister of Interior affairs and Public Health in the third and fourth cabinets of Georgi Kyoseivanov (November 1938 to February 1940).

Nedev was a friend of Petar Danov (also known by the name Beinsa Douno, and often called Master by his followers) who was a Bulgarian philosopher and spiritual teacher of the Universal White Brotherhood.

On 15 August 1907 Cadet Nedev graduated with excellence from the artillery class of the Higher Military School.

In 1911 Nedev was awarded an excellent mark in the entrance exam at the Higher Military Academy Еcole de guerre in Brussels, Belgium.

The war began after the controversy between the allied Balkan countries Bulgaria, Serbia, Montenegro, Greece and the Ottoman Empire could not be resolved by political and diplomatic means.

This artillery regiment was part of the Second Bulgarian Army, which besieged Edirne fortress whose defender was the "Feric" (Iron) Mehmed Shukri Pasha.

The Bulgarian and Serbian army, commanded by Major General Vladimir Vazov, carried out this tactic between 11 and 13 March 1913.

When the Great War began, he returned to Bulgaria and was chosen to be the battery commander in the Shumen fortress battalion.

Its task was to control the provisions of the Neuilly Peace Treaty, defining the territory, borders, reparations, and demilitarization.

The government chose Nedev for his reputation as a truly loyal, brave, military patriot, fluent French, Italian and German.

Between 25 August 1923 and 13 September 1924 Lieutenant Colonel Nedev was the commander of the 18th Infantry Battalion in Veliko Tarnovo.

While defending Dojran, Nedev came up with the idea to record the bravery of the Bulgarian soldiers of Pleven's regiment.

In 1927 Nedev published his second book Bulgaria in the World War – 1915–1918 a historical review, dedicated to "those who would continue the deeds of the whole Bulgarian nation".

In 1928 Nedev published the book The Liberation of Sofia a review of this unusual military operation in the winter of 1877.

After his return from Rome in 1932 Nikola Nedev was appointed commander of the 14th Macedonian Infantry Regiment in Gorna Dzhumaya.

At the time in the 12th Infantry Regiment in Stara Zagora, forty young soldiers were accused of communist activity.

Nedev stood by his men and said that he as general, would die with his soldiers, showing the world that people could be sentenced to death for their beliefs.

From 14 November 1938 Nedev was Minister of Interior Affairs and Public Health in the cabinet of Georgi Kyoseivanov.

On 31 July 1938 Bulgaria signed the Balkan Pact – its neighbors gave up the military restrictions of the Neuilly Treaty.

Nedev twice requested an audience with Tsar Boris III and insisted that no Jewish men who risked their lives for Bulgaria's freedom be sentenced to death.

After World War II, the new political forces in Bulgaria determined Major General Nikola Nedev to be a patriot and a humanist who typified the feats of the Bulgarian army.

– Erinnerungskreuz für die Unabhängigkeit Bulgariens – 1910 – Order of Bravery IV grade, 1st Class – 1917 – Order of Military Merit, II Grade – Order of St Alexander – Iron Cross, II Class – 1917 – 1921 – The Dojran epic – 1915–1918 – 1927 – Bulgaria in the World War – 1915–1918 – 1928 – The Liberation of Sofia – 1929 – The Wars of Liberation – 1877–1878, 1885, 1912–1913, 1915–1918 – Private archive of Nikola Nedev, Veliko Tarnovo – Memoir by Rousska Nikolova Nedeva-Koutzouglou – daughter of Nikola Nedev – Prof., Dr. Dimitar Kolev, memoir – Archives of the Ministry of Interior Affairs