Khamenia grew up North Hollywood, Los Angeles in and attends Harvard-Westlake School.

[2] Khamenia also plays for the Basketball Training Institute (BTI), an Amateur Athletic Union team, on the Puma Pro16 circuit.

[4][5] He committed to play college basketball at Duke over offers from UCLA and Gonzaga.

[6][7] Khamenia played for the United States under-18 basketball team at the 2024 FIBA Under-18 AmeriCup.

[8] He averaged 7.7 points, 6.3 rebounds, and 3.0 assists per game as the United States won the gold medal.