They were of major importance, serving under Grand Dukes of Bosnia/Serbia and noble families of Hranić and Kosača, lords of Hum and later Herzegovina.

[1][better source needed] Nikola had two sons by Katarina, the daughter of Stephen I, Ban of Bosnia: Vladislav and Bogiša.

Later, Vukosav participated in the Bosnian-Ragusan War around 1403 as a nobleman of the Grand Duke of Bosnia Sandalj Hranić, and was killed and buried in Ston on 28 November 1403.

The sons of Grgur Vukosalić, Vuk and Vukašin Grgurević, maintained their position under Stjepan Vukčić Kosača, as the Grand Duke tried to overtake Zeta.

The Ottoman Empire had already entered the area of Vrhbosna and prepared the conquest of the rest of the Bosnian Kingdom, which would occur 10 years later.