All conferences currently consist of four teams.

The conference alignment began in the 2022 season, although plans to have conferences were already set up before the inaugural season.

Named after the Nile River, the conference has been played at a single venue thus far, the Hassan Moustafa Sports Hall in Cairo, Egypt for the past two seasons.

From 2022 to 2024, all games of the Nile Conference were played at the Hassan Moustafa Sports Hall located in Cairo.

[a] Although no official trophy or title is awarded, the team ending at the top of the standings in the conference is lauded as "Conference winners" by the BAL.