Nishi-Mukō Station is served by the Hankyu Kyoto Line, and is located 33.6 kilometers from the terminus of the line at Jūsō and 36.0 kilometers from Osaka-umeda.

The station has two side platforms serving two tracks, connected by an underground passage.

This underground passage also functions as a general road connecting both sides of the station, and a partition in the center of the road separates the inside and outside of the station.

The station opened as Nishi-Mukōmachi Station on November 1, 1928, the day the Shinkeihan Line (present-day Hankyu Kyoto Main Line) was extended from Takatsuki-machi to Kyoto Saiin.

[1] In 1978 when the underground passage of the station was constructed, an archaeological excavation at the station found some ruins of Nagaoka-kyō, the capital city of Japan from 784 to 794, and earlier period.