It is operated by the private transportation company Hanshin Electric Railway.

[2] The station is called "Hanshin Nishinomiya" or "Han-Nishi" to distinguish the name from Nishinomiya Station on the JR West Tōkaidō Line (JR Kōbe Line) and Nishinomiya-kitaguchi Station on Hankyu Railway.

The station has two elevated island platforms serving four tracks.

Nishinomiya Station on the Hanshin Main Line opened on 12 April 1905.

[3] On 17 January 1995, the station was damaged by the Great Hanshin earthquake.