[3][4][5] Ganatra was educated at Coundon Court School and Community College on Northbrook Road and then studied Drama, Film, and Television at the University of Bristol.

He also appears in the Gurinder Chada film Bride and Prejudice as Kholi Saab and The Mistress of Spices as Haroun, and Dev Raja in Mumbai Calling.

[6] Other appearances include the television show Jane Hall, the Patents Clerk in Philip Pullman's The Shadow in the North, the CBBC television show Gina's Laughing Gear, a character in Meet the Magoons portraying himself, a semi lead role as Rez, brother of main character Shifty, in the 2008 British cult film Shifty about a Muslim crack-cocaine dealer, and Martin Soper in Twenty Twelve.

[9] It was announced in May 2017 that Ganatra would appear in comedy feature Eaten by Lions, alongside Antonio Aakeel and Jack Carroll.

[11] In 2020, he portrayed spell science teacher Mr. Daisy in the CBBC series The Worst Witch, and a lawyer in a two-part episode of Trial & Retribution.

[13] On 16 October 2007, Ganatra began playing regular character Masood Ahmed in the BBC One soap opera, EastEnders.

[16] At The British Soap Awards, Ganatra won Best On-Screen Partnership with Nina Wadia in 2009, and was nominated for Best Actor in 2010.