[1] Nitzanim was established on 8 December 1943 on a 400-acre plot of land purchased by the Jewish National Fund in 1942.

The kibbutz was bombarded and captured by the Egyptian army during the 1948 Arab–Israeli War in the Battle of Nitzanim.

[3] Following the war, the kibbutz was moved four kilometres south of the original location,[4] onto the land of the newly depopulated Palestinian village of Hamama.

[5] The original site of the kibbutz became Nitzanim Youth Village in 1949.

After the youth village closed in 1990, the community settlement of Nitzan was founded there.