He played college football for the Iowa Hawkeyes, and was selected by the Denver Broncos in the first round of the 2019 NFL draft.

[11] During Week 9 against the Cleveland Browns, Fant finished with three catches for 115 receiving yards, including a 75-yard touchdown as the Broncos won 24–19.

[12] During Week 14 against the Houston Texans, Fant finished with four catches for 113 yards and a touchdown as the Broncos won 38–24.

[16] In a Week 2 against the Pittsburgh Steelers, Fant caught four passes for 57 yards, a touchdown and a two point conversion during the 26–21 loss.

[18] In Week 6 of the 2021 season against the Las Vegas Raiders, Fant caught 9 passes for 97 yards and a receiving touchdown in the 34–24 loss.

In Week 17 against the Los Angeles Chargers, Fant caught 6 passes for 92 yards and a receiving touchdown in the 34–13 loss.