[3][2] Jupe started his acting career in 2015 by appearing in the television series Penny Dreadful and Downton Abbey.

[5] In 2017, he started his career in films, with his first major role being in The Man with the Iron Heart, a World War II drama.

[11] John Krasinski, who co-wrote and directed A Quiet Place, cast Jupe on Clooney's recommendation.

[19] He reprised his role as Marcus Abbott in A Quiet Place Part II later that year.

[20] In 2022, it was announced that he had been cast in the sci-fi drama film Morning, directed by Justin Kurzel.