Segan is the grandson of American photographer Arthur Rothstein and nephew of musician Rob Stoner.

[4] Segan has appeared in television programs, including Days of Our Lives, CSI: Crime Scene Investigation and House, and he provided the voice of Henry on the Nickelodeon series KaBlam!.

In 2008, Brick director Rian Johnson invited Segan to play a small role in his second film, The Brothers Bloom.

Segan joined the cast of Johnson's Knives Out in December 2018, playing the supporting role of Trooper Wagner.

Segan produced and starred in the independent feature films Redeemer, Some Kind of Hate, Quit, and Someone's Knocking at the Door, and has directed numerous music videos.