Co-written and co-produced by herself along with Andrej Hruška and Martin Šrámek, it was pre-released on November 7, 2011 as the second forerunner of the singer's then upcoming studio album Don't Look Back (2012), which followed a few months later.

Initially, the composition was specifically designed for the one-off compilation F84 (2011), performed by a number of her fellow recording artists, which as the first such collaborative effort in its country of origin helped raise awareness of those with autism.

Unlike its predecessor, "Nobody Knows" presented a downbeat R&B-oriented sound featuring elements including trip hop, electronica and some of techno riffs.

As disclosed by the producers Martin Šrámek and Andrej Hruška of the LittleBeat studio — both recognized as her regular tandem —, Buckingham was offered a chance to write a composition in support of children and adults affected by the symptoms of autism.

Featuring also vocal contributions by additional Slovak artists (such as e.g. Pavol Hammel), the release itself would be named after the so-called F84 syndrome, known as one of disorders of psychological development.

"[4] Honza Balušek writing for the online newspaper MusicServer.cz, refused the result for a change, calling it "[her] most weird [song]"[5] reportedly due to its "broken rhythm".

"[8] Apart from her younger sister Carmel, in a number of scenes also both co-writers and producers of the song Martin Šrámek and Andrej Hruška appeared in the video.